Metastatic Colorectal Cancer (liver and peritoneum)

About Metastatic Colorectal Cancer (Liver and Peritoneum)

Metastatic colorectal cancer occurs when cancer cells spread from the colon or rectum to other organs, most commonly the liver and peritoneum (lining of the abdominal cavity). This advanced stage often causes symptoms like abdominal pain, swelling, and weight loss. Treatment focuses on controlling disease progression and may include surgery, chemotherapy, targeted therapy, or a combination, aiming to improve survival and quality of life. Early detection of metastasis is crucial.

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Risk Factors

Advanced primary colorectal cancer stage
Delay in initial diagnosis or treatment
Poorly differentiated tumor cells
Presence of lymph node involvement
Inadequate or incomplete surgical removal of the primary tumor

Common Signs and Symptoms

Diagnosis of Metastatic Colorectal Cancer (Liver and Peritoneum)

Diagnosis involves a combination of imaging and laboratory tests. CT scans and MRI are commonly used to detect metastases in the liver and peritoneum. PET scans help identify active cancer spread. Blood tests, including liver function tests and tumor markers like CEA (carcinoembryonic antigen), support diagnosis and monitoring. A biopsy of metastatic lesions may be performed to confirm cancer spread and guide treatment decisions. Early and accurate diagnosis is essential for effective management.

Treatment Options

Treatment focuses on controlling the spread and improving quality of life:

Surgery

Removal of metastatic tumors in the liver or peritoneum when feasible.

Chemotherapy

Systemic treatment to target cancer cells throughout the body.

Targeted Therapy

Drugs that attack specific molecules involved in cancer growth.

Palliative Care

To manage symptoms and maintain comfort in advanced cases.

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